The accident which occurred on Wednesday, January 4, 2017, has been described as Uganda's deadliest road crash by the police.
The taxi reportedly rammed into two large vehicles killing eight people who died on the spot including a journalist.
The regional traffic police chief, Scovia Birungi said that six others reportedly died in the hospital.
Daily Post reports that nine others escaped with serious injuries while the cow was killed in the incident.
The crash reportedly took place along the Masaka-Kampala highway in Lwengo, on a stretch of road known locally as the most dangerous in Uganda.
Birungi said, “The accident took place when a speeding omnibus taxi avoided hitting a cow that was crossing the road, (and) rammed into a bus and a truck.
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“The vehicles crashed into each other, subsequently killing and injuring people. And the cow was not spared,” he added.
May the souls of the departed rest in peace.