In the Instagram post, shared Thursday afternoon, Kaley included multiple pictures of herself with Isaiah. "Tonights NEW episode @bigbangtheory_cbs is in honor of my sensational friend Isaiah @redguy29 !," Kaley wrote. "He has sat in the front row of our audience for the entire run of season 12."
Kaley went on to explain that Isaiah suffers from epidermolysis bullosa (EB), a rare genetic skin disorder (she tagged the Epidermolysis Bullosa Medical Research Foundation in her post, too).
"When I look into the crowd, he always has the biggest smile on his face," Kaley wrote about Isaiah. "He has become quite a key player here at BBT and I couldnt love him more. Isaiah, thank you for always reminding me how a smile can change an entire day. You are an inspiration and I will fight with you to find a cure!!"
I've never heard of epidermolysis bullosa-what is it?
Some people with the condition experience mild blisters, while others may deal with more severe blisters, some of which can form inside the body, in places like the tube that leads from the throat to the stomach, the mouth, and the bladder. In those cases, chewing and swallowing can be difficult, which can sometimes lead to nutritional issues.
Anyone can get epidermolysis bullosa, according to NIAMS, but symptoms usually first appear at the start of life, when patients are babies or toddlers.
While there's currently no cure for the condition, dermatologists and general practitioners can prescribe medications to help to reduce discomfort and prevent infection. In some cases, patients may need to undergo surgery to separate body parts like fingers and toes, that may have joined together by the blisters.
You'll have to wait until tonight's episode to see how The Big Bang Theory honors Kaley's friend, but from photos alone, I've got a feeling it'll put a big smile on Isaiah's face.
