"The warplane flew over us and directly started dropping its missiles on this hospital...at around 4 a.m.," Mohammad Abu Rajab, a radiologist at the M10 hospital, told Reuters. "The rubble fell in on the patients in the intensive care unit."

Since a ceasefire collapsed last week, rebel-held areas of Aleppo have been heavily bombarded, raising international concern over the plight of their 250,000 residents.