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Alessandra suffered from schizophrenia since she was 20, during her final decade she spent most of her time at the Blu Cammello workshop for adults with disabilities in Livorno, Italy, until her death in 2009.

Alessandra reportedly started creating art at the Blu Cammello, a workshop for adults with disabilities in 1999. Riccardo Bargellini, Director of visual Arts at Blu Cammello told   that amongst all of the patients with disabilities, Alessandra seemed like the most disturbed as she mostly keeps to herself.

"It was immediately clear that she would be a special case, among all the workshop participants, she certainly appeared to me as the most disturbed patient. I was only allowed to collect her drawings when they were finished," Riccardo said.

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Chris Byrne, author and curator who now manages Alessandra's estates explained that Alessandra lived in a private world which no one but Arts had access to.

"Alessandra appeared to live in a private world to which no one had access, with the ability to produce images quickly, she would often create drawings using both hands and her abrupt and confident mark-making always yielded a precise gesture," Chris said.

Alessandra was born in Livorno in 1961, where she'd spend the rest of her life. At 20 years old, she began to exhibit signs of schizophrenia following the death of her older sister. She subsequently spent the majority of her adult life in psychiatric facilities or residential mental health centers. In 1999, Michelangelo began creating art at Blu Cammelio, a workshop for adults with disabilities, and remained working there until her death ten years later.