The outspoken lawmaker believes the ruling party will eventually break up as internal division festers in the open.
The lawmaker took to his Twitter account (@dino_melaye) on Friday, November 9, to make the declaration.
"APC break up is unstopable. All promises cancel till we meet again," he posted.
The lawmaker's comment might be connected to the ongoing rumbling in the ruling party over the conduct of its primary elections.
Reports this week revealed that the party's chairman, Adams Oshiomhole, was questioned by the Department of State Services (DSS) over allegations made by certain governors that he received bribes to manipulate the APC's primary elections across the country.
The agency was also revealed to have compelled Oshiomhole to resign as the APC chairman, but he refused, noting that he still has President Muhammadu Buhari's confidence.
The primary elections of the APC to choose candidates to contest in the 2019 general elections has been trailed by a lot of divisions and controversies within the party.
A lot of state governors are openly feuding with Oshiomhole over what they've alleged to be his role in truncating the processes to install certain candidates.
His most notable feuds are with Ogun State governor, Ibikunle Amosun, Imo State governor, Rochas Okorocha, and Zamfara State governor, Abdulaziz Yari, who all failed in their bids to handpick their successors.
Melaye was elected as the representative of the Kogi West Senatorial district on the platform of the APC in 2015, but he publicly criticised the ruling party several times and openly feuded with Kogi State governor, Yahaya Bello.
He eventually dumped the APC to make a return to the PDP with dozens of other lawmakers in July 2018.