Jacques Brunel has largely kept faith with the Italy side that beat Scotland last time out in the Six Nations, with captain Sergio Parisse set to become the nation's record cap holder against France.
Parisse will turn out for the 112th time as the French visit the Stadio Olimpico, surpassing Marco Bortolami's record.
The three players to come into the side that beat Scotland 22-19 at Murrayfield are inside centre Andrea Masi, wing Leonardo Sarto and Fijian-born flanker Samuela Vunisa.
Masi and Sarto missed the Scotland clash through injury, while Vunisa makes just his fourth international appearance.
Italy team to face France: Luke McLean, Leonardo Sarto, Luke Morisi, Andrea Masi, Giovambattista Venditti, Kelly Haimona, Edoardo Gori, Matias Aguero, Leonardo, Ghiraldini, Dario Chistolini, George Biagi, Joshua Furno, Francesco Minto, Samuela Vunisa, Sergio Parisse.
Replacements: Andrea Manici, Alberto De Marchi, Lorenzo Cittadini, Quintin Geldenhuys, Marco Barbini, Guglielmo Palazzani, Tommaso Allan, Enrico Bacchin.
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