His journey to stardom kick-started with a film appearance in "Living in Bondage" as Chief Omego, a role which earned him a cash pay of N1,500.

In 2013, he received a political appointment from former President Goodluck Jonathan as a board member of the National Institute for Hospitality and Tourism Studies.

Now a renowned veteran, Kanayo O. Kanayo seeks to inspire the youth to great achievements, and provide a platform upon which they can more easily realize their dreams with a mentorship academy, Kanayo O. Kanayo Mentoring Academy, KOKMA.

In 2011, the actor contested to represent the people of Ahiazu/Ezinihitte Mbaise Federal Constituency at the House of Representatives.

His other works include  "Village Headmaster", "Television Play House", "At Your Service", "Checkmate", "Ripples" and others.