A day after Arsenal's home stumble against Bournemouth at the Emirates, Manchester City delivered a commanding second-half performance, narrowing the gap at the top of the Premier League to six points.
O'Reilly opened the scoring with a header shortly after the restart, before Guehi and Doku sealed a decisive 3-0 victory for Pep Guardiola's side, who are set to face Arsenal next week.
Guehi, a January acquisition, netted his second goal for the club, celebrating passionately before being named the Man of the Match.
However, he declined the award, instead handing it to teammate Cherki, who provided the assists for both his goal and O'Reilly's opener.
Guehi's gesture earned widespread praise from fans on social media, highlighting his humble character.