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Militants linked to the conflict across the border in Syria have carried out attacks in and around Arsal in the past.
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A roadside car bomb killed at least two people and wounded three on Thursday when it exploded in northeast Lebanon in an area close to the Syrian border, security sources and local media said.
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The bomb detonated in a commercial area of the Sabil neighbourhood of Arsal. It was not immediately clear what the target was.
Emergency services were working to rescue people from the rubble, the National News Agency said.
Islamist groups including al Qaeda's Nusra Front have a presence in western Syria, including near the border with Lebanon, and there are have been several incursions by militants reported in the region.
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