As they climbed to the top, Escobar and Guzman amassed obscene amounts of wealth and exposed the world to shocking horror.
Escobar's Medellin cartel and Guzman's Sinaloa cartel dealt in different products, faced different kinds of competition, and supplied different markets, but looking at them side by side gives a good idea of their power and their reach.
Pablo Escobar
Born into a modest farming family near Medellin in northern Colombia, Pablo Escobar started his career with petty crime but soon graduated to smuggling and eventually began carting shipments of marijuana.
Escobar's income is hard to measure, but it's believed he was raking in $420 million a week by the mid-1980s roughly $22 billion a year. By the end of that decade, he was supplying 80% of the world's cocaine and smuggling 15 tons of it into the US every day.
He spent lavishly on himself and his family and was a patron of local causes, building apartments and soccer fields and handing out cash to the poor. These acts won him popular support and bolstered his image as a man of the people.
"Pablo was earning so much that each year we would write off 10% of the money because the rats would eat it in storage or it would be damaged by water or lost," Escobar's brother Roberto wrote in a 2009 book .
Escobar's empire attracted the attention of the Colombian government, which attempted to shut it down. Clashes between the government and drug traffickers unleashed a years-long wave of violence in Colombia.
The Colombian government, with US assistance, deployed a special force to bring Escobar down, though that force was badly bloodied in its first encounter with the cartel. By mid-1991, the government's campaign forced Escobar to negotiate a deal that allowed him to lock himself up in a jail of his own design in the highlands near Medellin.
By the middle of 1992, evidence that Escobar was conducting cartel activity from his prison compelled the government to try to apprehend him. Instead, Escobar fled the prison and went on the run.
During this time, he and his family traveled from hideout to hideout, never staying in the same place for more than two days. At one point, Escobar torched $2 million in cash to keep his family warm.
He eventually began hiding out on his own but stayed in touch with his family, avoiding authorities' efforts to track him down with his communications. On December 2, 1993, his luck ran out . Colombian security forces believed to be working with Los Pepes, a vigilante group that was also tracking him converged on the Medellin home where he was staying.
When they burst through the door, Escobar scrambled onto the rooftop. Like many details of his life, it's unclear who fired the shot that killed the most powerful and most dangerous drug lord in the world.
Former Colombian President Cesar Gaviria, who oversaw Escobar's downfall, has told the world to not to fight drugs with the harsh measures he used, and the country's current president, Ivan Duque, took more concrete steps last month to break with the past, presiding over the demolition of Escobar's home in Medellin .
Joaquin El Chapo Guzman
Joaquin "El Chapo" Guzman was not the first drug baron to emerge from the Sierra Madre mountains of Sinaloa state in northwestern Mexico, but the cartel named for the state rose to global standing under his watch.
As the head of the Sinaloa cartel, Guzman oversaw marijuana and poppy cultivation throughout Mexico and drew on South American suppliers to sate appetites in the US, Europe, and Asia. At its peak the cartel had a presence in 24 of Mexico's 32 states and in as many as 50 countries, including an extensive network in the US.
At one point, cartel reportedly controlled 35% of the cocaine produced in Colombia and, according to the Drug Enforcement Administration, supplied 80% of the heroin, cocaine, marijuana, and meth flowing to the Chicago region of the US each year.
The Sinaloa cartel is also believed to have an immense international footprint. The cartel's activity has been reported in Australia, Hong Kong, and the Philippines. The cartel or people tied to it have appeared in West and North Africa .
In 1993, not long after reaching Sinaloa's upper ranks, Guzman fled to Guatemala after a shootout with rivals in Guadalajara killed a Catholic cardinal. He was caught in the Central American country and locked up in a Mexican prison.
He escaped in 2001, purportedly sneaking out while hiding in a laundry cart . That escape was reportedly arranged through state-security personnel working for Guzman, underscoring his allegedly expansive ties to the government. (A high-ranking security official at the prison was from Sinaloa state and later became Guzman's right-hand man in the cartel.)
He was on the run for 13 years before he was caught in Mazatlan, on Sinaloa's coast, in February 2014. After a 17-month stint in jail during which he continued his managerial duties he escaped again in spectacular fashion .
According to one report, his cartel henchmen dug a mile-long tunnel under the prison only to come up under the wrong part of the prison. Undetected and undeterred, they simply dug another tunnel , allowing Guzman to slip out, riding a modified motorcycle to a partially constructed house near the prison.
The Mexican government approved Guzman's extradition to US courts in Texas and California in late May 2016, and his lawyers responded with more appeals . But in the waning hours of President Barack Obama's term, Guzman was shuttled out of jail near Ciudad Juarez and onto a plane, emerging on Long Island, where US authorities took him to Manhattan and locked him up in one of the US's most secure facilities.
He spent more than a year under heavy guard and in near-total isolation before his trial began in November 2018.
During the three-month trial in Brooklyn he was carted back and forth from his cell during the proceedings prosecutors displayed evidence of a sprawling criminal organization that moved massive amounts of drugs, corrupted police and politicians at every level, and meted out brutal violence against rivals and bystanders.
Guzman was convicted on all counts in mid-February and will be sentenced in June. It's likely he will receive a life term to be served at ADX Florence, a maximum-security prison in Colorado called the " Alcatraz of the Rockies ."
Back in Mexico, the Sinaloa cartel weathered turmoil in the months following Guzman's arrest. Rivals challenged the control of Guzman's sons and Zambada, who reportedly joined forces to take over the organization.
In February 2017, Guzman's sons were ambushed by gunmen they said were working for Damaso Lopez Nuez, the former security official turned cartel member who rose to their father's right-hand man.
Guzman's sons and Zambada appear to have fended off challengers, who included rival cartels and factions led by Guzman's brother and by Lopez Nuez and his son, Damaso Lopez Serrano. (Both have been captured and are in the US; the elder Lopez testified against Guzman.)
Violence in Mexico has risen for several years , and some regions saw spikes in the months after Guzman's arrest, purportedly from fighting to fill the vacuum he left. Nationwide, violence continues to rise, but in Sinaloa state, the trend has reversed; that change has been attributed to renewed stability within the Sinaloa cartel, which now may be lashing out at rivals.
Less than two weeks after Guzman's conviction, Damaso Lopez Nuez's brother was gunned down in Sinaloa state, and in Guadalajara home turf of the Sinaloa cartel's main rival, the Jalisco New Generation cartel numerous " narcomantas " have appeared warning of a " cleansing ." The banners were attributed to Zambada.
"The Sinaloa cartel is conducting a retribution against Damaso's relatives for the attempted assassination of Mayo and Chapo's sons," said Mike Vigil, former chief of international operations for the DEA. "The other thing too is that the Sinaloa cartel is trying to basically wipe out the Jalisco New Generation cartel."
The Sinaloa cartel has never had the hierarchical structure of many of its competitors, functioning more like a federation of groups, overseen by Guzman and Zambada, who is thought to be about 70 years old. It remains powerful, but it and other large drug-trafficking groups like it may soon be things of the past.
"Zambada is not in good health ... so I think his days are numbered," Vigil said. "Chapo Guzman's sons really have never gotten their hands dirty. They were just thrust into the upper ranks of the cartel."
With Zambada gone and Guzman's inexperienced sons alone at the top, "then you're going to see the Sinaloa cartel diminish in terms of stature and in terms of capabilities," Vigil added, "and [it] will definitely fracture ... [and] have forces within that will break off."
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