Jadeveon Clowney's much-anticipated NFL debut was cut short on Sunday as the Houston Texans linebacker suffered a knee injury.
Clowney made one tackle, for a loss of nine yards, in the Texans season-opening 17-6 win over the Washington Redskins before being forced off the field with what is reportedly a torn meniscus.
It's more bad injury news for Clowney, who has not been a stranger in the trainer's room since being drafted No. 1 overall.
He revealed last week that he sustained a concussion during a pre-season joint practice with the Denver Broncos last month. In June, he underwent sports hernia surgery, having played through the pain of the injury during his junior year at South Carolina.
Now, he has a knee injury and could be out as long as six weeks.
"I don't know what happened on the field," Texans coach Bill O'Brien said after the game.
"I'm not sure what happened on that one. We're consulting with the doctors and trainers right now.
I'm not sure about the status, but I will say right now that they think it's a good prognosis so it looks like it's going to be ok.
"He may miss some time, he may not. Who knows. We'll know better as the week goes on.