The AFC and NFC championship games take place on Sunday, with the winners advancing to Super Bowl XLIX on February 1.
Three of the four quarterbacks remaining have already won the Super Bowl, and Andrew Luck is hoping to join that group that includes Tom Brady, Aaron Rodgers and Russell Wilson.
To do so, Luck will have to guide his Indianapolis Colts past Brady's New England Patriots.
"We're playing good team ball," said Luck, who threw for 370 yards and a pair of scores in Indianapolis' 24-13 win over Denver last Sunday. "We're feeding off each other. I'm so proud to be a part of it."
That Colts victory came against future Hall of Fame quarterback Peyton Manning. The next challenge is against another future Hall of Famer in Brady, a three-time Super Bowl champion.
The NFC title game features a pair of quarterbacks who have the highest postseason rating in league history.
Wilson, who helped lead the Seattle Seahawks to a Super Bowl title last year, and Rodgers, who guided the Green Bay Packers to a championship in 2010, are first and second on the all-time quarterback ranking list.
NFC Championship Game - Green Bay Packers (13-4) at Seattle Seahawks (13-4)
Rodgers has a torn calf muscle but helped the Packers to a come-from-behind 26-21 win over Dallas last Sunday. His injury could be an issue against an aggressive Seattle defense that finished the regular season as the league's top-rated unit.
"We're going to have to be efficient against them," Rodgers said. "They're a great defense, they've got Pro Bowlers all over the place and they're well-coached."
Green Bay boast two 1,000-yard receivers in Randall Cobb and Jordy Nelson, but it was rookie Davante Adams who came through against Dallas with seven catches for 117 yards and a touchdown. The Packers' pass-catchers will test a Seattle secondary that is the strength of the defense.
"We"re playing for each other," All-Pro cornerback Richard Sherman said. "That's been the biggest thing. Guys are doing whatever it takes to win. Guys are playing for one another, they don't care about stats. Championships are won in the playoffs."
Seattle have won seven straight games, including last week's 31-17 victory over Carolina, and are bidding to become the first back-to-back Super Bowl winners since the Patriots in 2004 and 2005.
"It's exciting but the job's not done," said Wilson. "We're on one mission. You just have to take it one game at a time. Our goal is to go 1-0."
AFC Championship Game - Indianapolis Colts (13-5) at New England Patriots (13-4)
Patriots coach Bill Belichick and Brady have been together in five Super Bowls, more than any other coach-quarterback combo. To extend that record, though, they will have to get past an upset-minded Colts team.
"That's what you play for," Belichick said. "You play to win your division, you play to be in the post-season and then you play to be in the AFC championship game and then you see what happens after that. It's great to have Tom and his ability and his poise and presence as our quarterback. Obviously he's done a tremendous job throughout the years. There's no quarterback I'd rather have than Tom Brady."
Brady threw three touchdowns in New England's 35-31 win over Baltimore last week. He now has an NFL-record 46 career postseason touchdown passes.
Luck has led the Colts to the playoffs in each of his first three seasons in the NFL and hopes to get Indianapolis back to the Super Bowl for the first time since 2006, when Peyton Manning led the franchise to a win over the Chicago Bears.
"The Patriots are a great, great team," Colts coach Chuck Pagano said. "Hall of Fame coach. Hall of Fame quarterback. We all know how hard it is to win there. We know it will be a tall order but it's going to be a great opportunity for our guys. We'll continue to embrace this opportunity and prepare accordingly."