We look at how events panned out in the build-up to the Russian's ban.
January 26 – Sharapova provides a urine sample at the 2016 Australian Open following her quarter-final defeat to Serena Williams.
March 7 – The former world number one announces she has been notified the ITF that she tested positive for meldonium, added to the World Anti-Doping Agency's list of prohibited substances on January 1 2016, at the Australian Open. A statement from the Tennis Anti-Doping Programme confirms she will be provisionally suspended from March 12.
March 8 – Nike suspends its sponsorship deal with Sharapova, while TAG Heuer postpones negotiations over renewing her contract and Porsche puts its planned activities with her on hold.
March 10 – Conversely, Head claimed it was "proud" to stand by the five-time grand slam champion and announced plans to extend her contract despite the failed drugs test.
March 11 – The Russian denies reports she was warned five times about meldonium use: "That is not true and it never happened," she wrote on Facebook.
March 12 – Sharapova's provisional suspension begins.
March 15 – The United Nations Development Programme (UNDP) confirms Sharapova has been suspended from her role as a goodwill ambassador.
May 3 – WADA announces 288 positive findings for meldonium have been recorded since it was banned on Janauary 1.
May 26 – Sharapova is included in Russia's squad for the 2016 Olympic Games in Rio de Janeiro despite being provisionally suspended.
June 8 – The 29-year-old is banned for two years from January 26, 2016, backdated due to her prompt admission. Sharapova confirmed she would immediately appeal to the Court of Arbitration for Sport.