Sam Warburton has urged his Wales team-mates to replicate the performance that saw them rout England two years ago.
Wales retained the Six Nations championship courtesy for a record 30-3 win in Cardiff in 2013 - their biggest ever victory against England.
The two nations will resume hostilities in the Welsh capital on Friday and skipper Warburton said Warren Gatland's side will be putting everything on the line.
"Two years ago, the fact we came out with such intensity was because it was a must-win game - the last of the championship - and we only had one opportunity to win by eight points or more to take the championship," Warburton said on Thursday.
"We have to treat this game with the same attitude as two years ago. It is a must-win fixture and it is that important.
"If we lose this one, we have three away games out of four to come and it is all uphill from there and extremely tough. It is important to win your home games."
Warburton added: "Some players might gain confidence out of beating (England), but in the last three years England and Wales have beaten each other home and away.
"It never feels as if there is more than a try in it either way, and we have been pretty evenly matched. They have won and lost at the Millennium Stadium, as we have at Twickenham.
"They have always been tight battles, and there may be a try in it on Friday night."