Liverpool's hopes of a Champions League place in all likelihood took a fatal hit with the Palace defeat.
Jurgen Klopp has failed to cure the Liverpool conundrum -- they go walkabout when playing the teams from the lower reaches.
Looking in control of Crystal Palace they allowed their lead to slip and woeful defending at a corner for the second saw old boy Christian Benteke head home to record a double.
Liverpool's hopes of a Champions League place in all likelihood took a fatal hit with the Palace defeat but similar losses throughout the season like against Bournemouth have also done untold damage.
Until Klopp solves the problem Liverpool will not be realistic title challengers.
Jose Mourinho's style may agitate many especially with his criticism of Luke Shaw and then Anthony Martial but it appears to have had a marked effect on both players.
Martial responded with a goal and a key role in the second in the 2-0 win over Burnley that gives real hope for United to finish in the top four and secure a Champions League place through that route.
The only people who on Sunday may not have been as happy will be the United accountants as Martial's goal cost them an extra 10 million euros and enriched Monaco's coffers at the same time.
Regardless of Gaston Ramirez's 20th minute sending off, Middlesbrough were already 2-0 down to Bournemouth and whilst manager Steve Agnew urged his troops to rally for the midweek game with bottom side, and north-east rivals, Sunderland victory would probably just be for bragging rights as both look destined for the second tier.
'Boro are nine points adrift of safety -- and still without a league win in 2017 the only side in the top European leagues to have the unwanted tag -- and with Hull especially in good order catching them looks beyond a side whose paucity of invention and goals has cost them dearly.
Hull showed Middlesbrough that being reduced to 10 men is no barrier to victory as Oumar Niasse's first-half expulsion did more to energise Hull than it did a lacklustre Watford outfit who looked like they are eyeing the beach already.
Since Marco Silva took over in January, Hull have taken on a different look in both style and morale and have dropped just two points at home. That could ultimately prove the difference between the drop and staying up.
After a rocky run of form the team delivered the win manager Paul Clement demanded, a 2-0 win over a wasteful Stoke side.
If the Swans are to beat the drop, though, they will require leading scorer Fernando Llorente -- who got their first on Saturday -- to stay fit.
Even more crucially will be that playmaker Gylfi Sigurdsson maintains his high standards as he has all but singlehandedly been the driving force that has kept their hopes alive of retaining their spot amongst the elite this season.