Barcelona will take on Valencia and Sevilla meet Celta Vigo in the Copa del Rey semi-finals.
Barcelona will face Valencia in the semi-finals of the Copa del Rey.
The holders overcame Athletic Bilbao in the quarter-finals and have been pitted against Gary Neville's side, who defeated Las Palmas, in the last four.
Celta Vigo, who pulled off a shock by beating Atletico Madrid in the last eight, will face Sevilla in the other semi-final, after Unai Emery's side knocked out surprise package Mirandes.
The first legs will be played at Camp Nou and the Ramon Sanchez Pizjuan on February 3, before the return legs one week later.