He said Misau's claims have seriously damaged his reputation and caused him considerable distress.
Senator Misau has been involved in a very public spat with the IGP who he has accused of several corrupt practices including collecting bribes on several occasions.
In the suit, the IGP also asked that the lawmaker representing Bauchi Central Senatorial District be made by the court to tender a public apology to him in two widely read national daily newspapers, as well as an order of injunction restraining Misau from further making similarly defamatory accusations.
Among a list of the IGP's grievances with the lawmaker is the accusation that he received bribes from police officers in exchange for assigning them favourable promotions.
He told the court that in a news report entitled "Police Officers pay bribe for special promotion - Senator", published in the Daily Trust on August 10, Misau had been quoted as saying, "You are talking about N500,000, it's beyond that. A serving police officer aware of the trend has told me that they pay as much as N2.5m to get special promotion. Other sources have also confirmed to me. So it is nothing but fact."
The IGP also raised objection to the lawmaker's accusation that he collected N120 billion from oil firms, corporate bodies and highly placed individual citizens for special security service provided by the Nigeria Police Force (NPF).
The IGP also referred to Misau's allegations of his perceived nepotism to be false and malicious and that they portray him as a corrupt public officer who is involved in crimes and criminality of bribery and corruption.
In his lawsuit, he noted that Misau's claim that he makes undue gain of N10 billion monthly as the head of the NPF has seriously damaged his reputation and caused him considerable distress, embarrassment, shame, odium, anxiety, anguish, opprobrium and injury to his feelings.
The suit will be heard by Justice Jude Okeke on November 13.
In a separate case, the office of the Attorney-General of the Federation has also filed a suit against Misau over what it described as false allegations against the Police Force and the IGP.