Exercise may affect how and when we move, even when we aren’t exercising, according to a fascinating new study in mice.
Exercise may affect how and when we move, even when we aren’t exercising, according to a fascinating new study in mice. The findings suggest that, by influencing our built-in body clocks, exercise may help our bodies to recognize the optimal times we should be moving, and when we should be still.
Most of us have heard of circadian rhythms. Our heartbeats, hormones, hunger, alertness, digestion, fatigue and other bodily functions move through regular cycles on a schedule that is both predictable and syncopated, changing as circumstances demand.
But probably few of us realize that physical activity, both in people and most animals, likewise tends to follow a broad, circadian pattern.
Most obviously, we tend to sleep at night, hardly moving, and be active during the day.
But during the day, too, physical activity by people usually shows certain patterns, although those patterns noticeably change with age, recent science shows.
The graphs showed that the young people moved quite a bit during the day, with frequent peaks and valleys in their activities. These patterns weren’t neatly consistent; some days someone might sit and barely move early in the day, and on other days he or she might be moving early on and quiet later.
But there was generally an internal logic to the movement, the scientists concluded. If someone had been still for some time, he or she then would start moving; and if someone had just moved or exercised a lot, he or she often would take some time to settle, since presumably the body was still physiologically aroused, but would then be still.
In essence, the young people’s bodies seemed to be somehow remembering and responding to what that body had just been doing, whether sitting or moving, and then calculating a new, appropriate response — moving or sitting. In doing so, the researchers felt, the body created a healthy, dynamic circadian pattern.
They also gave the animals running wheels, because exercise can so dramatically increase the difference between activity and quiet and has many effects within the body that can influence daily movement.
They let the animals run at will for a month.
Unsurprisingly, the young mice, which ran quite a bit, rapidly developed substantial peaks and valleys of activity, with clear demarcations between the movements associated with daytime and night.
The older animals had similar, but more blunted patterns.
Then the scientists removed the wheels.
Within days, all of the animals began showing more random patterns of movement. They might suddenly race around the cage during what should have been their quiet period or crouch unmoving when they would normally have been active.
And most interesting, the patterns of the young mice and the old mice were much more alike than they had been before.
That finding suggests, that exercise affects daily movement patterns more than age does. Take away a young mouse’s running wheel and its activity patterns will look similar to that in an older animal.
However, as soon as the researchers restored the running wheels to the animals’ cages, both young and old mice began exercising again and had soon reinstated their old, healthy patterns of movement. Elderly mice had some peaks and valleys, and the young mice many.
Of course, exercise by definition influences how much activity someone completes during the day. But the research believe that something deeper and more interesting also occurs with exercise. It seems to affect the body’s internal clock mechanisms and therefore its circadian rhythms, especially those related to activity. It may keep those patterns healthier, even with age.
By prompting the release of a wide variety of biochemicals in the body and brain, he suggested, exercise almost certainly affects the body’s internal clock mechanisms and therefore its circadian rhythms, especially those related to activity. Exercise seems to make the body better able to judge when and how much more it should be moving and when it should be at rest.
Of course, this study was short-term, involved mice rather than people, and wasn’t designed to identify just how exercise might affect the body’s internal clocks, the research points out.
But it does suggest that, among its many virtues, exercise improves the rhythm of our lives.
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