After 10 years, the actress whose contract was up for renewal this season, confirmed that she will not be back for Season 13.

In season 12 finale, her character was written out as she proceeded to travel to NYC with Sophia.

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Reacting to Callie's exit, Shonda Rhimes tweeted;

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In April, Sara Ramirez posted a cryptic Tweet, teasing her exit from show.

Ramirez exit marks the third major exit on show, following the departures of Sandra Oh in Season 10 and Patrick Dempsey in Season 11.

Following the death of undefined, fans launched a undefinedto bring back his character.

Watch a "Greys Anatomy" clip below.