Ryan Reynolds is a gambler in 1st trailer for movie

Watch two gamblers hit the road to pay back a giant debt in upcoming dramedy ''Mississippi Grind.'

Ryan Reynolds and Ben Mendelsohn are two expert gamblers in upcoming drama 'Mississippi Grind.'

Ryan Reynolds and Ben Mendelsohn are two expert gamblers in upcoming drama 'Mississippi Grind.'

Synopsis.

Convinced that his newfound friend (Ryan Reynolds) is a good-luck charm, a gambling addict (Ben Mendelsohn) takes the man on a road trip to a high-stakes poker game in New Orleans.

Directed by Ryan Fleck and Anna Boden, 'Mississippi Grind,' also stars Sienna Miller, Analeigh Tipton, Robin Weigert and Alfre Woodard.

'Mississippi Grind' opens in theaters on September 25.

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