Nico Rosberg called for answers from his Mercedes team after being forced to retire in the 14th lap at Sunday's Singapore Grand Prix.
Radamel Falcao made his expected full United debut, replacing the in-form Juan Mata, with captain Wayne Rooney eased back into a slightly deeper role.
The German suffered problems throughout his short-lived race as he was forced to relinquish second place on the grid after suffering electronic failure on the parade lap.
Having started from the pit lane, Rosberg's race also ended there as further issues prevented him from changing gear after a pit stop.
His retirement allowed team-mate Lewis Hamilton to move top of the overall standings going into the final five races of the calendar and Rosberg is eager for an explanation.
"It wasn't so much a roller coaster ride because it was all downhill for me," he told BBC Radio 5 live.
"It was very frustrating to drive behind a Caterham and sit on a grid and watch everyone else leave. But that is the way it is.
"I was stuck with no power, only able to shift gear pedals, but even there not every gear. It was all over the place.
"The steering wheel did not work and then the whole car wasn't working. We need to find out what the problem was because again we have a reliability problem.
"We've had a few this year and that's our weakness. We need to get to the bottom of it and make the car 100 per cent reliable.
"It's tough not even leaving the grid. I was hoping the team could fix it [after the race had started] because it was going on and off, sometimes working, sometimes not.
"There's no point in shouting, it's a reliability issue, and it's happened again."