Loose forward Kriel tore knee ligaments playing in Japan and will be out of action for up to eight weeks
Loose forward Kriel tore knee ligaments playing in Japan and will be out of action for up to eight weeks, a South Africa Rugby statement said.
France-based tighthead Du Plessis, a 2007 Rugby World Cup winner, wants to be with his wife, who is expecting their third child soon.
Adriaanse and Carr were originally chosen for an exhibition match against the Barbarians at Wembley Stadium in London on November 5, but not for Tests in England, Italy and Wales.
Coach Allister Coetzee said Du Plessis remained part of his plans as he tries to revive the Springboks, who have lost five of nine Tests this season.
"Jannie has a wealth of experience, a burning desire to still be part of the Springboks, and has a lot to offer us."
South Africa play England in London on November 12, Italy in Florence on November 19 and Wales in Cardiff on November 26.
The Springboks hold a final training session in Johannesburg Friday before flying to London in the evening.
Revised South Africa Test squad
Forwards (18): Lourens Adriaanse, Willem Alberts, Nizaam Carr, Eben Etzebeth, Lood de Jager, Steven Kitshoff, Vincent Koch, Malcolm Marx, Bongi Mbonambi, Oupa Mohoje, Franco Mostert, Tendai Mtawarira, Trevor Nyakane, Jean-Luc du Preez, Roelof Smit, Adriaan Strauss (capt), Pieter-Steph du Toit, Warren Whiteley
Backs (15): Damian de Allende, Ruan Combrinck, Faf de Klerk, Johan Goosen, Bryan Habana, Elton Jantjies, Jesse Kriel, Patrick Lambie, Lionel Mapoe, Rudy Paige, Sergeal Petersen, JP Pietersen, Willie le Roux, Francois Venter, Piet van Zyl
Coach: Allister Coetzee