Tottenham saw Kane equalise and then win the game in added time thanks to another disputed penalty.
Harry Kane scored two late goals as Tottenham Hotspur came from behind to beat West Ham 3-2 on Saturday in a bad-tempered derby that featured two controversial penalty awards by referee Mike Dean.
Dean, already known to be the most zealous official when it comes to enforcing this season's directive to clamp down on grappling in the box, penalised Spurs's Vincent Janssen for impeding Winston Reid in the 67th minute at White Hart Lane.
That allowed West Ham's Manuel Lanzini to add to Michail Antonio's first-half opener for the visitors.
But Tottenham, for whom Harry Winks scored on his first Premier League start, saw Kane equalise and then win the game in added time thanks to another disputed penalty.
Dean has now awarded nine penalties this season, more than any other Premier League official, having previously penalised Manchester City's Raheem Sterling and Charlie Daniels of Bournemouth for off-the-ball offences other referees might well have let go.
And just before Saturday's final whistle, Dean also sent off Reid for a clash with Kane.
Winks, the 20-year-old midfielder, fired an early chance wide as Tottenham made the livelier start.
Christian Eriksen found the net from Spurs' next attack, slotting past Darren Randolph, in for Adrian in the West Ham goal, but it was correctly ruled out for offside.
Sppurs felt they should have had a penalty for Pedro Obiang's manhandling of Harry Kane but Dean wasn't interested.
West Ham had already shown they were keen to attack, however, and Antonio cut inside from the right to fire just over.
Antonio saw an effort from closer range deflected behind for a corner that Cheikhou Kouyate headed against the bar in the 24th minute. Reid was first to the rebound to set up the alert Antonio to nod in.
Lanzini was booked for upending Danny Rose as Tottenham sought a reply but only a free-kick was awarded when Janssen sent Cheikhou Kouyate flying off the pitch and on to a set of water bottles in front of enraged Hammers boss Slaven Bilic.
Mousa Dembele was shown a yellow card however for a barge on Diafra Sakho, in his first game of the season, but Dimitri Payet's free-kick flicked off the wall.
The half-time whistle was greeted with jeers by some home fans, who hadn't had a shot on target to cheer in the previous 45 minutes.
Spurs were level, however, in the 51st minute.
Janssen's fierce shot was parried by Randolph at his near post but Winks was first to the rebound and despatched it despite the goalkeeper getting a touch.
That sparked Tottenham into life and West Ham survived two penalty appeals for handball before Randolph did well to block Eric Dier's header with his foot.
Rose was booked for fouling Antonio, whose revenge on the left-back saw Eriksen fire a free-kick just over.
Then it was the turn of Dean to make the headlines, the referee pointing to the spot when Reid went down with Janssen's arms all over him.
Lanzini made no mistake with the penalty, in the 68th minute, and the Dutchman was immediately replaced by Spurs manager Mauricio Pochettino with Dele Alli.
West Ham tried to pick Spurs off on the counter-attack but to no avail and it was the hosts who scored the game's remaining goals.
Kane made it 2-2 with two minutes remaining with a back-post finish after Randolph could only spoon out a cross by Son Heung-Min, the substitute.
Then, in stoppage time, Hammers substitute Havard Nordtveit tangled with Son on the edge of the box and again Dean pointed to the spot, for Kane to win a game that ended with Reid shown a red card.