SportyBet have a Madrid win at (1.18), which is also the likeliest of outcomes.
But the Meringues play in front of home fans with the league title at stake, especially after the slip up against rivals Barcelona a week ago - in the 'El-Clasico'.
Certainly a high scoring game looks likely, but it’s hard to look past Real Madrid for the win as they are coming off a 6-2 win at Deportivo La Coruna.
It's (11.83) to back a Valencia win, and (3.42) says they are the first team to score just like in the last encounter.
Los Blancos have played 27 games so far this season that have had over 2.5 total goals, and Valencia compliment that fact, having done same in 14 of the 21 games they've been involved in this year. Over 2.5 goals is priced at (1.16).
The Real Madrid players have managed to score 90 goals this season, and Cristiano Ronaldo tops their list of scorers with 31 goals this term.
The forward is the likeliest to score in this game at (1.25).
Valencia's top choices are Simone Zaza (3.25), Munir El Haddadi Mohamed (3.70) and Santiago Mina Lorenzo (3.75).
Striker Simone Zaza scored first in the fourth minute of the last league game against Madrid, and SportyBet is offering a whooping (11.71) for him to do the same in this game.
World's best player Ronaldo is also tipped to be the first goalscorer of the game at (3.17), followed by Morata at (3.51) , and Benzema at (3.98).
Wales international Gareth Bale and Portugal's Pepe are both out injured.
Full-back Fabio Coentrao is a doubt for this game and most likely won't play a part as Marcelo has been outstanding in Madrid's recent games.
Valencia will be without defender Aymen Abdennour and Rodrigo, while Joao Cancelo is serving match suspension.