Turkish media report that six people have been confirmed injured in the bomb blast.
BBC reports that the explosion was an alleged suicide bomb attack which has left one person dead.
Further reports by the Turkish media say six people have been confirmed injured in the bomb blast.
Frequently hosting tourists - especially on weekends - the attack on Istiklal Street, is coming barely a week after an attack in the capital, Ankara, killed 37 people.
The attack was claimed by a Kurdish militant group, saying it was in revenge for Turkish military operations against Kurds.